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A high MPV with a low platelet count may indicate that the platelets you make are going into circulation very quickly. A low MPV is linked to ... What does it mean if your MPV blood test results are high? A high test result means that your platelets are larger than what's considered normal. Newly made ... High MPV is linked to inflammation and conditions like cardiovascular disease. Larger platelets tend to clump together, forming clots. While ... MPV. Automated hematologic ... Defective platelet production: Abnormal platelet production due to defective megakaryocytes can result in a high MPV. A high MPV seems to be associated with a cardiovascular risk and an increased risk of thrombosis (phlebitis, etc.). In a person who has no history of bleeding ... However, having a high or low MPV doesn't confirm anything and should be interpreted with CBC test results. Common Causes of MPV Blood Test. The mean platelet volume (MPV) test measures the average size of your platelets, tiny blood cells crucial for clotting and stopping bleeding. thrombocytosis – an increased number of platelets. CBC results can be low or high for many reasons. Some examples of abnormal CBC results related to cancer are ... The RDW can help differentiate the cause of anemia: eg, a high RDW suggests iron-deficiency anemia, while a nor- mal RDW suggests thalassemia. High or low platelet levels can be a sign of a severe condition. The mean platelet volume (MPV) blood test is typically part of a complete blood count (CBC) ...